Hairy cell leukaemia

Hairy cell leukaemia

Rare but often very treatable with the purine analogue cladrabine

Look long and hard for them in all patients with cytopenia(s) especially where there is also splenomegaly

These lymphocytes:

  • are medium sized
  • have fine irregular projections
  • contain a condensed nuclear chromatin structure and absent nucleoli
  • are often very few in the peripheral blood

What is the classical pattern by immunophenotyping/flow cytometry? 


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