Red cell Inclusions
- Single, dark inclusion located at the periphery of mature red cells.
- It is formed from remnant DNA usually removed by the spleen.
- Associated features that may also be seen include target cells, thrombocytosis, and pan-leucocytosis.
- after surgical splenectomy
- functional hypo or asplenism states associated with sickle cell disease,
- thalassaemia, and coeliac disease
Figure 2.22 - Howell-Jolly body (blood)